5-MTHF 5 mg
Support your mood, heart health, foetal development, and nerve function with active folate. 5-MTHF is a ready-to-use, essential B vitamin that promotes heart, brain, and blood health.
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Key Benefits
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Supports brain function and mood.
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Facilitates healthy methylation and homocysteine levels.
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Supports women's health and foetal development.
5-MTHF is the biologically active methylated form of folate that the body’s tissues can readily utilise. Many individuals do not receive sufficient 5-MTHF due to factors such as intestinal or liver dysfunction, or because they fall within the 60% of Americans who have genetic variations that hinder the conversion of folic acid into active 5-MTHF.
Adequate levels of 5-MTHF are essential for the production of key neurotransmitters like serotonin, melatonin, dopamine, and epinephrine, which are essential for maintaining healthy brain function and mood. In conjunction with vitamin B12, 5-MTHF serves as a vital methyl-group donor, promoting healthy methylation processes and balanced homocysteine levels. Adequate folic acid intake is especially important before conception and during early pregnancy, as its highest demand occurs during the first trimester, often before a woman realises she is pregnant. A deficiency in folic acid is associated with an increased risk of low-birth-weight infants and neural tube defects.
Thorne’s formula delivers 5 mg of active 5-MTHF to support foetal development and enhance heart, brain, and blood health. Its advanced formulation ensures maximum absorption in a small, easy-to-take capsule.
Thorne’s 5-MTHF supplement is the top choice for those seeking the highest quality in nutritional support. Each capsule contains the most absorbable form of methylated folate, ideal for individuals with MTHFR gene mutations, ensuring that the body receives maximum benefit with minimal effort. Crafted from clinically researched, sustainably sourced ingredients, Thorne’s 5-MTHF is designed for optimal absorption, safety, and efficacy to deliver exceptional results.
Thorne sets the standard for excellence in the supplement industry. Recommended by over 100 professional sports teams and U.S. National Teams, Thorne offers a curated bundle of clean, science-backed supplements and treats designed to fuel your body naturally and effectively. With more than 30 years of dedication to quality, Thorne's commitment to purity and potency begins with sustainably sourced ingredients and rigorous testing. Every supplement undergoes four rounds of testing to ensure optimal absorption, safety, and efficacy, making Thorne the trusted choice for both health-conscious individuals and professionals.
With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.
Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.
Folate (L-5-MTHF) 8.3mg DFE, Hypromellose Capsule, Leucine, Microcrystalline Cellulose, and Silicon Dioxide.
Interactions:
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
Shipping
At Healf, we prioritize safe and fast delivery for all our customers. Our carefully selected couriers are Royal Mail and DPD.
UK standard delivery
Enjoy free standard delivery on orders above £50, this option usually requires 2-3 working days. If your order is under £50, this delivery option is available for £3.99.
Next working day
For when you need our products urgently, we offer next working day shipping for £5.99. For orders placed before 12.00, we will ship it the same day to ensure you receive your order the next working day.
International
International deliveries can take 7 working days, and up to 4 weeks. The cost is £22.99 for orders below £50, £49.95 for orders above.
Returns
If for any reason you are not satisfied with your order, we provide free 365-day UK returns for all our customers. To initiate your return, simply contact us at team@healf.com, and we'll send you a return slip and help arrange a collection. The item you return must be sent in the same condition as received and inside the original packaging. Once received, we will notify you via email.
For international returns, we unfortunately do not cover the cost. However, we work with an array of carriers and can offer self-posting returns for customers shopping from outside the UK.
Take one capsule 1-2 times per day.
Recommended to take with a meal.
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Frequently asked questions
Every product undergoes our Healf Curation Process. With it, you can shop confidently knowing that every item has been tried and tested before it reaches you. Our Healf Curation Process includes three key steps: Brand Discovery, Expert Validation, and Community Testing. Through these, we assess quality, ingredients, effectiveness, and more, ensuring that every product empowers your wellbeing.
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100+ health markers.
Two annual at-home blood tests.
Personalised product recommendations.
Healf Curation
Process™
Every product undergoes our rigorous Healf Curation Process, ensuring you are always getting the best when it comes to your wellbeing.
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Expert Validation
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