Primeadine® GF Gluten-Free Spermidine

This gluten-free spermidine formula features a unique chlorella sub-strain, selected from over 100 for its high spermidine and putrescine content—key polyamines for cellular health. Grown in Okinawa, Japan, this chlorella benefits from nutrient-rich conditions and sunlight exposure, boosting its chlorophyll, vitamins D and K, which support calcium absorption into bones. Complementing this are two potent autophagy inducers and anti-inflammatories: Okinawan turmeric and nobiletin from Shikuwasa citrus lime peel.

And unlike others, it avoids synthetic enrichment, ensuring only natural, food-derived spermidine. Raw materials are sourced from Japan, renowned for its autophagy research and strict quality controls. Each batch undergoes testing for purity and potency, manufactured under ISO22000 standards. Free from synthetic additives, Primeadine® ensures a clean, vegan-friendly formula, delivering high-quality spermidine that is both effective and reliable.

Leslie Kenny founded Oxford Healthspan, inspired by her remarkable journey of overcoming autoimmune conditions through natural health solutions. Partnering with Oxford University scientists, Leslie discovered spermidine, a natural longevity compound, and launched the flagship product, Primeadine®. Today, the brand offers premium, food-derived spermidine supplements, empowering individuals with scientifically-backed tools to support cellular health and promote vibrant ageing.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Primeadine® GF contains Okinawan Chlorella (whole, broken cell wall), Shikuwasa Citrus Peel, and Turmeric, providing naturally-occurring: Spermidine (1.6mg), Lutein (2.57mg), Nobiletin (0.3mg); Vitamins and Minerals: Vitamin D2 (7mcg), Vitamin K (6mcg), Folate (25mcg), Vitamin B12 (0.09mcg), Biotin (3mcg), Pantothenic Acid (0.04mg), and Iron (0.3mg).
Other Ingredients: Tricalcium Phosphate.

Shipping

At Healf, we prioritize safe and fast delivery for all our customers. Our carefully selected couriers are Royal Mail and DPD.

UK standard delivery

Enjoy free standard delivery on orders above £50, this option usually requires 2-3 working days. If your order is under £50, this delivery option is available for £3.99.

Next working day

For when you need our products urgently, we offer next working day shipping for £5.99. For orders placed before 12.00, we will ship it the same day to ensure you receive your order the next working day.

International

International deliveries can take 7 working days, and up to 4 weeks. The cost is £22.99 for orders below £50, £49.95 for orders above.

Returns

If for any reason you are not satisfied with your order, we provide free 365-day UK returns for all our customers. To initiate your return, simply contact us at team@healf.com, and we'll send you a return slip and help arrange a collection. The item you return must be sent in the same condition as received and inside the original packaging. Once received, we will notify you via email.

For international returns, we unfortunately do not cover the cost. However, we work with an array of carriers and can offer self-posting returns for customers shopping from outside the UK.

2 tablets per day, with water at your first or last meal. You may also grind tablets and add to smoothies.

First Time Use: On your first day, take 1 tablet and if well-tolerated, continue with the recommended dose.