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TMG Methylation Essentials
A comprehensive methylation support formula combining TMG with essential nutrients in acid-resistant capsules for healthy ageing and DNA protection.
Free sample each month
Pause or cancel anytime
365 day free returns
Back in stock: 28/06/2025
Buy now, pay later from £9.37/mo with
Free UK shipping over £50, free returns.
Key Benefits
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Supports methylation and gene regulation.
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Promotes cellular repair and energy production.
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Helps balance homocysteine levels.
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Enteric coating protects against stomach acid.
TMG Methylation Essentials delivers a carefully crafted blend of nutrients designed to support methylation, a fundamental process for healthy ageing and cellular function.
This formula features Trimethylglycine (TMG), a natural methyl donor that supplies crucial methyl groups for DNA repair, cellular energy, and gene expression. Alongside TMG, it includes Folate, Vitamin B6, Vitamin B12, and Zinc, which are essential cofactors that keep methylation pathways working smoothly and efficiently.
As we age, methylation pathways can become less effective, impacting cellular health and contributing to higher homocysteine levels, a risk factor for numerous health concerns. By supporting methylation balance, this formula helps protect against DNA methylation alterations that are associated with ageing and chronic disease.
To ensure the nutrients reach the small intestine intact, TMG Methylation Essentials uses acid-resistant enteric capsules that protect the active compounds from stomach acid and release them only in the small intestine for maximum absorption and effectiveness.
TMG Methylation Essentials stands out for its use of Acid Resistant™ Enteric capsules, engineered to protect the active ingredients as they pass through the harsh, acidic environment of the stomach. These capsules remain intact until they reach the more alkaline conditions of the small intestine, where they safely release their contents for optimal absorption. This targeted delivery system ensures the nutrients are efficiently absorbed and used by the body, maximising their benefits for methylation support, DNA repair, and healthy ageing.
Bryan Nettles founded Renue by Science back in 2017, inspired by his passion for research and science regarding healthy ageing. In addition to fitness, diet, and sleep, supplements have played an essential role in his life. Bryan’s mission is to educate and motivate people to live long and strong lives. Today, Renue by Science offers the highest quality, most comprehensive range of bioavailable longevity products at the best possible price. They work with leading experts and doctors to stay updated on the latest research, using these insights and customer feedback to bring you the most effective solutions available.
With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.
Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.
Vitamin B6 (as Pyridoxine HCL), Folate (as 5-Methyltetrahydrofolate Calcium), Vitamin B12 (as Pure Methylcobalamin), Zinc las Zinc Picolinate), TMG (Trimethylglycine) (as Betaine Anhydrous), AR-CAPS®, Acid Resistant Capsules, Rice Flour, Microcrystalline.
Shipping
At Healf, we prioritize safe and fast delivery for all our customers. Our carefully selected couriers are Royal Mail and DPD.
UK standard delivery
Enjoy free standard delivery on orders above £50, this option usually requires 2-3 working days. If your order is under £50, this delivery option is available for £3.99.
Next working day
For when you need our products urgently, we offer next working day shipping for £5.99. For orders placed before 12.00, we will ship it the same day to ensure you receive your order the next working day.
International
International deliveries can take 7 working days, and up to 4 weeks. The cost is £22.99 for orders below £50, £49.95 for orders above.
Returns
If for any reason you are not satisfied with your order, we provide free 365-day UK returns for all our customers. To initiate your return, simply contact us at team@healf.com, and we'll send you a return slip and help arrange a collection. The item you return must be sent in the same condition as received and inside the original packaging. Once received, we will notify you via email.
For international returns, we unfortunately do not cover the cost. However, we work with an array of carriers and can offer self-posting returns for customers shopping from outside the UK.
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Frequently asked questions
Every product undergoes our Healf Curation Process. With it, you can shop confidently knowing that every item has been tried and tested before it reaches you. Our Healf Curation Process includes three key steps: Brand Discovery, Expert Validation, and Community Testing. Through these, we assess quality, ingredients, effectiveness, and more, ensuring that every product empowers your wellbeing.
The Healf Journal offers detailed insights into different aspects of wellbeing, as well as guidance, research, recipes, and more to help you invest in your personal wellbeing journey. You can also subscribe to our weekly newsletters for the latest updates at Healf and in the wellbeing industry. Subscribe via the sign-up block at the bottom of this page.
We love people who check ingredients as carefully as we do, so you'll find detailed information about the ingredients used on every product page (where applicable). If you see something you'd like to flag with us or have additional questions, please don't hesitate to get in touch—we'd love to hear from you.
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