Key Benefits

• Feel energised—B6, B12, and Folate contribute to normal energy-yielding metabolism and help reduce tiredness and fatigue.

• Stay sharp and resilient—Zinc supports normal cognitive and immune system function.

• Promotes healthy cell division and DNA synthesis with Folate, B12, and Zinc.

• Betaine, B6, Folate, and B12 contribute to normal homocysteine metabolism.

• Acid-resistant capsules protect nutrients for optimal absorption.

Start your day with confidence—TMG Methylation Essentials brings together Trimethylglycine (TMG), Folate, Vitamin B6, Vitamin B12, and Zinc in a formula designed to fit seamlessly into your routine.

Each capsule delivers nutrients that work in harmony: B6, B12, and Folate help unlock energy from your food and support the reduction of tiredness and fatigue, while Zinc contributes to normal DNA synthesis and cognitive function. Betaine, B6, Folate, and B12 all play a role in maintaining normal homocysteine metabolism, supporting your body’s natural balance.

Folate, B12, and Zinc also have a role in the process of cell division, helping to keep your cells functioning as they should. The advanced acid-resistant capsules ensure these nutrients reach your small intestine, where they’re best absorbed—so you get the most from every dose.

Choose TMG Methylation Essentials for a simple, science-backed way to support your daily wellbeing.

TMG Methylation Essentials stands out for its use of Acid Resistant™ Enteric capsules, engineered to protect the active ingredients as they pass through the harsh, acidic environment of the stomach. These capsules remain intact until they reach the more alkaline conditions of the small intestine, where they safely release their contents for optimal absorption. This targeted delivery system ensures the nutrients are efficiently absorbed and used by the body, maximising their benefits for methylation support, DNA repair, and healthy ageing.

Bryan Nettles founded Renue by Science back in 2017, inspired by his passion for research and science regarding healthy ageing. In addition to fitness, diet, and sleep, supplements have played an essential role in his life. Bryan’s mission is to educate and motivate people to live long and strong lives. Today, Renue by Science offers the highest quality, most comprehensive range of bioavailable longevity products at the best possible price. They work with leading experts and doctors to stay updated on the latest research, using these insights and customer feedback to bring you the most effective solutions available.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Vitamin B6 (as Pyridoxine HCL), Folate (as 5-Methyltetrahydrofolate Calcium), Vitamin B12 (as Pure Methylcobalamin), Zinc las Zinc Picolinate), TMG (Trimethylglycine) (as Betaine Anhydrous), AR-CAPS®, Acid Resistant Capsules, Rice Flour, Microcrystalline.

Take two (2) capsules daily with or without food.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.

Store in a cool, dry place. Do not use if safety seal is broken or missing.

Additional Information:

Food supplements and foods sold by Healf should not be used as a substitute for a varied, balanced diet and healthy lifestyle.

If you are pregnant, breastfeeding, have a medical condition, or are taking any medications, please consult with a healthcare professional before use. Use products only if the seal is intact. Store in a cool, dry place, out of the reach of young children. Do not exceed the recommended daily intake.

We make every effort to ensure that product information on our website is accurate and up to date, but packaging and ingredients may occasionally vary from images shown on site. Please refer to the product label and contact Healf before use if you have any questions regarding your specific allergies or intolerances.