Key Benefits

• Gentle cleanses and exfoliates the skin.

• Enhances the efficacy of OS-1 peptides.

• Dermatologically tested and safe for all skin types.

PREP is a gentle daily facial cleanser designed to effectively remove impurities, light makeup, and sunscreen while preserving your skin’s natural barrier. Formulated with six active ingredients, it exfoliates, cleanses, and conditions your skin for a fresh, healthy glow.

Breu Branco acts as an antioxidant exfoliant, neutralising free radicals and providing anti-inflammatory benefits. Arnica Extract stimulates microcirculation and hydrates irritated skin, while Japanese Honeysuckle Extract delivers natural antioxidant and detoxifying properties. Prickly Pear Extract gently removes dead skin cells and soothes irritation, aided by its flavonoids that help with sunburn recovery. Niacinamide enhances skin texture by promoting healthy protein synthesis, and Sodium Grapeseed Amidopropyl PG-Dimonium Chloride Phosphate offers antioxidant power 50 times stronger than vitamins C or E.

PREP also primes your skin for the next steps in your OS-1 routine. When used with other OneSkin topical products, such as the peptide eye cream, peptide face cream, and daily facial sunscreen (all sold separately), it enhances the effectiveness of OS-01 peptides by 2x.

Dermatologically tested and suitable for all skin types, including acne-prone and combination skin, this cleanser is the perfect first step towards achieving a healthy, radiant complexion.

OneSkin’s products harness the power of OS-01, an innovative peptide that tackles skin’s biological age by zeroing in on senescent cells—often referred to as "zombie" cells that speed up the ageing process. As these damaged cells accumulate, they lead to wrinkles, loss of firmness, and thinning skin. The OS-01 peptide works by actively repairing DNA damage in these cells, stopping them from unleashing harmful pro-aging factors that can impact surrounding healthy cells. This groundbreaking approach reduces cellular senescence, effectively lowering the skin’s biological age. It also boosts biomarkers of healthy skin, including collagen and hyaluronic acid biosynthesis to promote a healthier, more youthful skin that stays resilient over time.

Founded by a team of four female PhDs, OneSkin's products focus on skin longevity. At the core of their products is OS-01, the only peptide scientifically proven to reverse skin aging at the molecular level. OneSkin's approach goes beyond aesthetics, focusing on keeping skin healthier and more resilient over time. With rigorous research, peer-reviewed data, and a passion for life, the brand is redefining ageing and empowering individuals to live without limits.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Water, Sodium Laurylglucosides Hydroxypropylsulfonate, Cocamidopropyl Hydroxysultaine, Disodium Lauryl Sulfosuccinate, Glycerin, Sodium Hydroxypropylphosphate Laurylglucoside Crosspolymer, Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Breu Branco Resin, Caprylyl Glycol, Phenoxyethanol, Lonicera Japonica (Honeysuckle) Flower Extract, Niacinamide, Sorbic Acid, Arnica Montana (Arnica Flower) Extract, Tetrasodium Glutamate Diacetate.

Lather 1-2 pumps of PREP daily facial cleanser in damp hands until a light foam is formed.
Gently massage onto lightly wet skin on the face and neck.
Rinse thoroughly and pat skin dry.
Follow with the remainder of your routine Use 2 times daily.

Pro tip: Designed to gently remove dead skin cells, dirt, oil, makeup, and sunscreen, PREP cleanser doubles the penetration 01 of OS-01 FACE (sold separately) when used together.