Key Benefits

• Plant-based formula with concentrated Japanese wheat germ extract.

• Includes FOS prebiotic fibre from beetroot to complement your routine.

• Each serving delivers 1mg of naturally sourced spermidine.

• Vegan-friendly and contains 40mg of gluten per serving.

Support your daily wellbeing with Primeadine® Original, a thoughtfully crafted spermidine supplement from Oxford Healthspan. Each serving provides 1mg of plant-derived spermidine, sourced from defatted Japanese wheat germ extract for purity and freshness.

With added FOS prebiotic fibre from beetroot, this formula fits easily into a balanced lifestyle. Spermidine is a naturally occurring polyamine found in wheat germ, and FOS prebiotic fibre is included to complement your daily nutrition.

Primeadine® Original brings together plant-based spermidine and prebiotic fibre in a clean, effective blend—designed for those seeking a mindful addition to their daily routine.

Every dose offers a simple way to include these ingredients in your day, supporting your commitment to wellbeing.

Primeadine® Original stands apart with its unique formulation and rigorous sourcing standards. It features FOS (fructooligosaccharide) prebiotic fibre, which supports gut bacteria that naturally produce spermidine, enhancing both supplemental and endogenous spermidine levels. Unlike others, it avoids synthetic enrichment, ensuring only natural, food-derived spermidine. Raw materials are sourced from Japan, renowned for its autophagy research and strict quality controls. Each batch undergoes testing for purity and potency, manufactured under ISO22000 standards. Free from synthetic additives, Primeadine® ensures a clean, vegan-friendly formula, delivering high-quality spermidine that is both effective and reliable.

Leslie Kenny founded Oxford Healthspan, inspired by her remarkable journey of overcoming autoimmune conditions through natural health solutions. Partnering with Oxford University scientists, Leslie discovered spermidine, a natural longevity compound, and launched the flagship product, Primeadine®. Today, the brand offers premium, food-derived spermidine supplements, empowering individuals with scientifically-backed tools to support cellular health and promote vibrant ageing.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Each serving provides 1mg of plant-derived spermidine from concentrated, defatted Japanese wheat* germ extract. Defatting removes omega-6 fatty acids, reducing the risk of rancidity and inflammation.
Other ingredients: Prebiotic Fiber (FOS) from Resistant Dextrin (Beetroot), Hypromellose (Vegan Cellulose Capsule), Sodium Citrate.

Allergens: Wheat (Contains 40mg of gluten). In comparison, the average slice of bread contains 1,000-2,000mg of gluten.

3 capsules per day, taken with water at your first or last meal.
On day one, start with 1 capsule; if well-tolerated, continue with the full dose.

Additional Information:

Food supplements and foods sold by Healf should not be used as a substitute for a varied, balanced diet and healthy lifestyle.

If you are pregnant, breastfeeding, have a medical condition, or are taking any medications, please consult with a healthcare professional before use. Use products only if the seal is intact. Store in a cool, dry place, out of the reach of young children. Do not exceed the recommended daily intake.

We make every effort to ensure that product information on our website is accurate and up to date, but packaging and ingredients may occasionally vary from images shown on site. Please refer to the product label and contact Healf before use if you have any questions regarding your specific allergies or intolerances.