Key Benefits

• Plant-based blend with naturally-occurring vitamin D, vitamin K, folate, vitamin B12, biotin, pantothenic acid, and iron.

• Supports your immune system, energy release, and normal bones, skin, and hair.

• Helps reduce tiredness and fatigue, so you can feel your best every day.

• Contributes to normal psychological and cognitive function for daily wellbeing.

Start your day with confidence—Primeadine® GF is a gluten-free, plant-based supplement crafted by Oxford Healthspan. Each serving features Okinawan chlorella, a freshwater algae, alongside nobiletin from Okinawan citrus peel and turmeric. This carefully selected blend is certified gluten-free and made without wheat-based ingredients, making it a thoughtful choice for those with gluten sensitivities.

Every dose delivers a spectrum of naturally-occurring vitamins and minerals. Vitamin D and vitamin K contribute to the maintenance of normal bones and support your immune system. Folate and vitamin B12 help reduce tiredness and fatigue, while biotin and iron support normal energy-yielding metabolism and the maintenance of normal hair and skin. Pantothenic acid contributes to normal mental performance, and iron supports normal cognitive function.

With 1mg of naturally-occurring spermidine per serving, Primeadine® GF offers a plant-based option to help you maintain your daily wellbeing and feel ready for whatever comes next.

This gluten-free spermidine formula features a unique chlorella sub-strain, selected from over 100 for its high spermidine and putrescine content—key polyamines for cellular health. Grown in Okinawa, Japan, this chlorella benefits from nutrient-rich conditions and sunlight exposure, boosting its chlorophyll, vitamins D and K, which support calcium absorption into bones. Complementing this are two potent autophagy inducers and anti-inflammatories: Okinawan turmeric and nobiletin from Shikuwasa citrus lime peel.

And unlike others, it avoids synthetic enrichment, ensuring only natural, food-derived spermidine. Raw materials are sourced from Japan, renowned for its autophagy research and strict quality controls. Each batch undergoes testing for purity and potency, manufactured under ISO22000 standards. Free from synthetic additives, Primeadine® ensures a clean, vegan-friendly formula, delivering high-quality spermidine that is both effective and reliable.

Leslie Kenny founded Oxford Healthspan, inspired by her remarkable journey of overcoming autoimmune conditions through natural health solutions. Partnering with Oxford University scientists, Leslie discovered spermidine, a natural longevity compound, and launched the flagship product, Primeadine®. Today, the brand offers premium, food-derived spermidine supplements, empowering individuals with scientifically-backed tools to support cellular health and promote vibrant ageing.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Primeadine® GF contains Okinawan Chlorella (whole, broken cell wall), Shikuwasa Citrus Peel, and Turmeric, providing naturally-occurring: Spermidine (1.6mg), Lutein (2.57mg), Nobiletin (0.3mg); Vitamins and Minerals: Vitamin D2 (7mcg), Vitamin K (6mcg), Folate (25mcg), Vitamin B12 (0.09mcg), Biotin (3mcg), Pantothenic Acid (0.04mg), and Iron (0.3mg).
Other Ingredients: Tricalcium Phosphate.

2 tablets per day, with water at your first or last meal. You may also grind tablets and add to smoothies.

First Time Use: On your first day, take 1 tablet and if well-tolerated, continue with the recommended dose.

Additional Information:

Food supplements and foods sold by Healf should not be used as a substitute for a varied, balanced diet and healthy lifestyle.

If you are pregnant, breastfeeding, have a medical condition, or are taking any medications, please consult with a healthcare professional before use. Use products only if the seal is intact. Store in a cool, dry place, out of the reach of young children. Do not exceed the recommended daily intake.

We make every effort to ensure that product information on our website is accurate and up to date, but packaging and ingredients may occasionally vary from images shown on site. Please refer to the product label and contact Healf before use if you have any questions regarding your specific allergies or intolerances.